The Adrenal Stress Index (ASI) uses five conveniently collected saliva samples to assess cortisol, insulin, DHEA/DHEA-S, secretory IgA, 17-OH progesterone, and wheat gluten sIgA. Saliva is collected over a period of 24 hours, providing more complete information about your body’s stress response than a single test. This is ideal for people dealing with chronic stress and stress-related symptoms such as insomnia, anxiety and fatigue. ASI is a comprehensive panel that will give your provider better measurements and greater context for your hormone levels than standard serum and urine testing. With more information, your provider will be able to treat your symptoms more efficiently.

Tests Included

Cortisol	Evaluates stress response
Insulin	Investigates blood sugar control and insulin resistance
DHEA/DHEA-S	Determines how other hormones may be affected by stress
Total secretory IgA (sIgA)	Evaluates the toll of stress on immunity
17-OH Progesterone	Determines underlying causes of abnormal cortisol levels
Wheat gluten sIgA	Identifies immune response to gluten

The Adrenal Stress Index can be helpful for people experiencing:

Chronic stress and stress-related health conditions
Fatigue or lack of energy
Anxiety or depression
Irritability or mood swings
Insomnia, sleep disturbances or difficulty waking
Poor memory or difficulty retaining information
Muscle and joint pain or weakness
Blood sugar dysregulation
Osteopenia or osteoporosis
Changes in skin integrity, easy bruising or excessive stretch marks
Frequent or chronic infections
Hypertension
Increased waist-to-hip ratio or abdominal obesity

Why use our Adrenal Stress Index (ASI)?

Saliva is the best method for measuring free, active levels of cortisol
The collection process is noninvasive and painless
Samples can be collected anywhere (home, office or anywhere in between)
24-hour measurement provides a more complete image of your body’s stress response

Clinical Applications of the Adrenal Stress Index (ASI)

Sleep Disorders
Sleep disorders are a very common concern. A disordered circadian rhythm can be a significant contributing factor to sleep difficulties. The ASI measures cortisol levels throughout the day and evening which can help to identify these abnormal patterns. Identification of aberrant circadian rhythms are key to proper understanding and subsequent treatment of sleep difficulties.

Glycemic Dysregulation
Chronic elevations in cortisol (often due to prolonged stress) increase blood glucose by increasing the rate of gluconeogenesis in the liver. Recurring exposure to high cortisol may potentially lead to insulin resistance. The ASI investigates the insulin-cortisol relationship under real-life conditions to allow targeted and effective interventions. This panel may be useful in many clinical situations including rapid weight gain or obesity, abnormal blood lipid levels, muscle wasting, early diabetes, or associated symptoms.

Allergies & Autoimmune Disorders
More than fifty years ago, it was noted that people with environmentally-triggered allergies and autoimmune diseases dramatically improved when given cortisol for other purposes. By providing information about dynamic cortisol levels, the ASI may help to identify people with autoimmune diseases and adrenal problems who may improve with cortisol optimization.

Other Disorders
The ASI can be a useful tool for evaluating people with many different medical conditions. Many publications describe a hyperactive HPA axis in patients with depression. Elevated salivary cortisol can be an important screening tool for Cushing’s syndrome and Cushing’s disease. In Addison’s disease, abnormally low levels of cortisol are produced. Other cortisol abnormalities have been correlated with attention deficit hyperactivity disorder (ADHD). Anomalous cortisol findings such as these, as well as those frequently seen in depression, can be identified using the ASI panel.

Collection: DiagnosTechs

Filter and sort

Filter

Adrenal Stress Index (ASI)

Adrenal Stress Index (ASI)