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Pregnenolone, MS
Great reasons to buy from us:
Pregnenolone
What is it: Pregnenolone is a steroid prohormone that leads to the production of progesterone, mineral corticoids, glucocorticoids, androgens, and estrogens. In humans, steroid hormones are produced by the adrenal glands and the gonads. The formation of Pregnenolone from cholesterol is the first step in steroid genesis and is mediated by the proteolytic enzyme, single cholesterol side-chain cleavage enzyme (P450 scc). Steroid genesis continues along two paths from Pregnenolone. By the enzymatic action of 17α-hydroxylase (17α-H) and 3β-hydroxysteroid Dehydrogenase (3β-HSD) 17-Hydroxypregnenolone and progesterone are produced, respectively.
Tested for: identifying the effects of increased cortisone demand, insufficient hormone production
Increased in: Since the various forms of congenital adrenal hyperplasia (CAH) result from enzymatic defects in the adrenal steroidogenic pathways, elevated levels of Pregnenolone levels may be useful in their diagnosis.
Decreased in: Levels can be suppressed with dexamethasone inhibition and increased with exogenous ACTH stimulation.
Info: Pregnenolone levels have been shown to remain in the normal range in patients with Cushing syndrome and hyperaldosteronism.
Estimated between and
Will usually ship within 1 business day.
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Please allow 10 days for your order to arrive. We source products from all over the world to bring you epic offers and the lowest prices. This means sometimes you have to wait a little longer to get your order but it's always worth it! |
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 |
Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap! |
 |
We Put Our Customers First to us. If it doesn't fit, it breaks, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund you every cent. |
|
 |
Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap! |
|
 |
In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down. |
|
 |
We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again. |
|
 |
Ordering from Shoptimized is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone either. |
Pregnenolone
What is it: Pregnenolone is a steroid prohormone that leads to the production of progesterone, mineral corticoids, glucocorticoids, androgens, and estrogens. In humans, steroid hormones are produced by the adrenal glands and the gonads. The formation of Pregnenolone from cholesterol is the first step in steroid genesis and is mediated by the proteolytic enzyme, single cholesterol side-chain cleavage enzyme (P450 scc). Steroid genesis continues along two paths from Pregnenolone. By the enzymatic action of 17α-hydroxylase (17α-H) and 3β-hydroxysteroid Dehydrogenase (3β-HSD) 17-Hydroxypregnenolone and progesterone are produced, respectively.
Tested for: identifying the effects of increased cortisone demand, insufficient hormone production
Increased in: Since the various forms of congenital adrenal hyperplasia (CAH) result from enzymatic defects in the adrenal steroidogenic pathways, elevated levels of Pregnenolone levels may be useful in their diagnosis.
Decreased in: Levels can be suppressed with dexamethasone inhibition and increased with exogenous ACTH stimulation.
Info: Pregnenolone levels have been shown to remain in the normal range in patients with Cushing syndrome and hyperaldosteronism.
Estimated between and
Will usually ship within 1 business day.
|
Please allow 10 days for your order to arrive. We source products from all over the world to bring you epic offers and the lowest prices. This means sometimes you have to wait a little longer to get your order but it's always worth it! |
|
|
Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap! |
|
We Put Our Customers First to us. If it doesn't fit, it breaks, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund you every cent. |
|
|
Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap! |
|
|
In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down. |
|
|
We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again. |
|
|
Ordering from Shoptimized is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone either. |
