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EstroVantage EM 90 vcaps

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$ 41.00
 
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EstroVantage EM 90 vcaps

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$ 41.00
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In general, estrogen can be divided into several biochemically distinct hormones: estrone (E1), estradiol (E2), estriol (E3), and 17-estradiol. In premenopausal women, estrogen is enzymatically converted to several specific estrogen metabolites including 2-hydroxyestrone (2-OHE1), 2-hydroxyestradiol (2-OHE2), 4-hydroxyestrone (4-OHE1), 4-hydroxyestradiol (4-OHE2) and 16a-hydroxyestrone (16a-OHE1). Both 16a-OHE1 and 2-OHE have contrasting biological activities at the cellular level with 16a-OHE1 being an estrogen agonist and proliferative, while 2-OHE is an estrogen antagonist and antiproliferative. As such, an increased ratio 2-OHE:16a-OHE1 is associated with a reduced risk of invasive breast cancer risk in premenopausal women. Several natural products found in EstroVantage EM support this latter concept including DIM, and indole 3 carbinol (I3C). A human study has confirmed that daily supplementation with 300 mg of I3C daily for 12 weeks significantly increased the 2-OH-estrone: estriol metabolite ratio without notable adverse events. Other compounds in EstroVantage EM, including calcium-d-glucarate, inhibit beta-glucoronidase activity, allowing for the excretion of estrogen before reabsorption. It is estimated that a 4% calcium glucarate supplemented diet inhibits beta-glucuronidase activity by 70%.

Benefits
IGF-1 has a known pathogenic role in cancer, increasing growth of existing cancer cells. Lycopene supplementation decrease IGF-1 by 25%.
In a 34 patient randomized controlled trial foods enriched with bioactive compounds, including rosemary extract (Rosemarinus officinalis), were found to be a promising adjuvant therapy in advanced breast cancer patients
Green tea polyphenols inhibit the proliferation of breast cancer cells in vivo and in
vitro
Silymarin can down-regulate gene products involved in the proliferation of tumor cells (cyclin D1, EGFR, COX-2, TGF-beta, IGF-IR), invasion (MMP-9), angiogenesis (VEGF) and metastasis (adhesion molecules)
Curcumin inhibits human breast cancer cell growth by mediating certain signaling cascades including the modulation of the NF-kB signaling pathway
Sulforaphane can inhibit the expression of estrogen receptor alpha (ERalpha) protein in MCF-7 cells, inhibiting proliferation and down-regulating hormone receptor expression
Standardized extracts

Servings Per Container: 30

Take 3 capsules per day taken with food or as directed by a health care professional. Consult a health care professional for use beyond 12 weeks.


Serving Size: 3 capsules

Amount Per Serving:
Calcium D-Glucarate
 ... 225mg
(d-glucaric acid calcium salt)
Indole-3-Carbinol ... 225mg
(3-hydroxymethylindole)
Green Tea Extract ... 150mg
(Camellia sinensis)(leaf)
(80% catchins, 45%EGCg <1% caffeine)
Tomato Extract ... 150mg
(Lycopersicon esculentum)(fruit)
(5% lycopene)
Broccoli Powder ... 83mg
(Brassica oleracea var. italica)(aerial)
(0.36% sulforaphane)
Turmeric Extract ... 75mg
(Curcuma longa)(root)
(95% curcuminoids)
Milk Thistle Extract ... 75mg
(Silybum marianum)(seed)
(60% silymarin)
DIM ... 75mg
(3, 3-diindolylmethane)
Rosemary Extract ... 38mg
(Rosmarinus officinalis)(leaf)

Other Ingredients: Vegetarian capsule
(Carbohydrate gum [cellulose]. purifed
water), microcrystalline cellulose and
magnesium stearate (vegetable grade)

Other Shoppers Viewed
Shipping
 This item Ships to 
Delivery

Estimated between  and

Will usually ship within 1 business day.

   

Please allow 10 days for your order to arrive. We source products from all over the world to bring you epic offers and the lowest prices. This means sometimes you have to wait a little longer to get your order but it's always worth it!

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap!

Here are 5 more great reasons to buy from us:

   

We Put Our Customers First to us. If it doesn't fit, it breaks, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund you every cent.

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap!

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Shoptimized is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone either.

In general, estrogen can be divided into several biochemically distinct hormones: estrone (E1), estradiol (E2), estriol (E3), and 17-estradiol. In premenopausal women, estrogen is enzymatically converted to several specific estrogen metabolites including 2-hydroxyestrone (2-OHE1), 2-hydroxyestradiol (2-OHE2), 4-hydroxyestrone (4-OHE1), 4-hydroxyestradiol (4-OHE2) and 16a-hydroxyestrone (16a-OHE1). Both 16a-OHE1 and 2-OHE have contrasting biological activities at the cellular level with 16a-OHE1 being an estrogen agonist and proliferative, while 2-OHE is an estrogen antagonist and antiproliferative. As such, an increased ratio 2-OHE:16a-OHE1 is associated with a reduced risk of invasive breast cancer risk in premenopausal women. Several natural products found in EstroVantage EM support this latter concept including DIM, and indole 3 carbinol (I3C). A human study has confirmed that daily supplementation with 300 mg of I3C daily for 12 weeks significantly increased the 2-OH-estrone: estriol metabolite ratio without notable adverse events. Other compounds in EstroVantage EM, including calcium-d-glucarate, inhibit beta-glucoronidase activity, allowing for the excretion of estrogen before reabsorption. It is estimated that a 4% calcium glucarate supplemented diet inhibits beta-glucuronidase activity by 70%.

Benefits
IGF-1 has a known pathogenic role in cancer, increasing growth of existing cancer cells. Lycopene supplementation decrease IGF-1 by 25%.
In a 34 patient randomized controlled trial foods enriched with bioactive compounds, including rosemary extract (Rosemarinus officinalis), were found to be a promising adjuvant therapy in advanced breast cancer patients
Green tea polyphenols inhibit the proliferation of breast cancer cells in vivo and in
vitro
Silymarin can down-regulate gene products involved in the proliferation of tumor cells (cyclin D1, EGFR, COX-2, TGF-beta, IGF-IR), invasion (MMP-9), angiogenesis (VEGF) and metastasis (adhesion molecules)
Curcumin inhibits human breast cancer cell growth by mediating certain signaling cascades including the modulation of the NF-kB signaling pathway
Sulforaphane can inhibit the expression of estrogen receptor alpha (ERalpha) protein in MCF-7 cells, inhibiting proliferation and down-regulating hormone receptor expression
Standardized extracts

Servings Per Container: 30

Take 3 capsules per day taken with food or as directed by a health care professional. Consult a health care professional for use beyond 12 weeks.


Serving Size: 3 capsules

Amount Per Serving:
Calcium D-Glucarate
 ... 225mg
(d-glucaric acid calcium salt)
Indole-3-Carbinol ... 225mg
(3-hydroxymethylindole)
Green Tea Extract ... 150mg
(Camellia sinensis)(leaf)
(80% catchins, 45%EGCg <1% caffeine)
Tomato Extract ... 150mg
(Lycopersicon esculentum)(fruit)
(5% lycopene)
Broccoli Powder ... 83mg
(Brassica oleracea var. italica)(aerial)
(0.36% sulforaphane)
Turmeric Extract ... 75mg
(Curcuma longa)(root)
(95% curcuminoids)
Milk Thistle Extract ... 75mg
(Silybum marianum)(seed)
(60% silymarin)
DIM ... 75mg
(3, 3-diindolylmethane)
Rosemary Extract ... 38mg
(Rosmarinus officinalis)(leaf)

Other Ingredients: Vegetarian capsule
(Carbohydrate gum [cellulose]. purifed
water), microcrystalline cellulose and
magnesium stearate (vegetable grade)

Other Shoppers Viewed
Shipping
This item Ships to   
Delivery

Estimated between  and

Will usually ship within 1 business day.

   

Please allow 10 days for your order to arrive. We source products from all over the world to bring you epic offers and the lowest prices. This means sometimes you have to wait a little longer to get your order but it's always worth it!

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap!

Here are 5 more great reasons to buy from us:

   

We Put Our Customers First to us. If it doesn't fit, it breaks, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund you every cent.

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap!

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Shoptimized is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone either.

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