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Tru Niagen Pro 300

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$ 49.00
 
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Tru Niagen Pro 300

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$ 49.00
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Take an active role in helping maintain your health, longer [1-3]. TRU NIAGEN® PRO delivers the highest dose of nicotinamide riboside (NR) per capsule available today. It’s key ingredient is backed by multiple published human trials, and is clinically proven to increase nicotinamide adenine dinucleotide (NAD)[4-6], the critical catalyst that powers metabolism and helps maintain healthy cellular function.*

Adults take One capsule per day or as recommended by your healthcare professional.

Serving Size: 1 Vegetarian Capsule

Amount Per Serving
NIAGEN® ... 300mg
(nicotinamide riboside chloride)

Other Ingredients: Microcrystalline Cellulose, Hypromellose (Vegetarian Capsule).

NIAGEN® and TRU NIAGEN® are trademarks of ChromaDex, Inc.
If you are pregnant, nursing, or taking any medications, please seek the advice of a healthcare professional prior to use. Not intended for use by children under 18. Store in original container in a cool, dry place.

NAD has been shown to decline with age [7, 8] and metabolic stress [9-12]. It has also been shown to help support many aspects of healthy aging.

Tru Niagen Pro provides daily cellular care to help you age better® and live better, including:

  • Replenishing NAD levels[4, 6, 13, 14]*
  • Increasing cellular energy production[14]*
  • Promoting healthy cellular metabolism[15-17]*
  • Promoting cellular repair[7, 15, 17, 18]*
  • Supporting healthy aging[4, 6, 13, 14]*
References
  1. Rajman, L., K. Chwalek, and D.A. Sinclair, Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell Metab, 2018. 27(3): p. 529-547.
  2. Verdin, E., NAD(+) in aging, metabolism, and neurodegeneration. Science, 2015. 350(6265): p. 1208-13.
  3. Yoshino, J., J.A. Baur, and S.I. Imai, NAD(+) Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab, 2018. 27(3): p. 513-528.
  4. Airhart, S.E., et al., An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers. PLoS One, 2017. 12(12): p. e0186459.
  5. Martens, C.R., et al., Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults. Nat Commun, 2018. 9(1): p. 1286.
  6. Trammell, S.A., et al., Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nat Commun, 2016. 7: p. 12948.
  7. Massudi, H., et al., Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One, 2012. 7(7): p. e42357.
  8. Zhou, C.C., et al., Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. Br J Pharmacol, 2016. 173(15): p. 2352-68.
  9. Canto, C., et al., The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metab, 2012. 15(6): p. 838-47.
  10. Gariani, K., et al., Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice. Hepatology, 2016. 63(4): p. 1190-204.
  11. Seyssel, K., et al., Regulation of energy metabolism and mitochondrial function in skeletal muscle during lipid overfeeding in healthy men. J Clin Endocrinol Metab, 2014. 99(7): p. E1254-62.
  12. Wang, S., et al., Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1alpha/mitochondrial biosynthesis pathway. Redox Biol, 2018. 17: p. 89-98.
  13. Dollerup, O.L., et al., A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects. Am J Clin Nutr, 2018.
  14. Martens, C.R., Denman, B.A., Mazzo, M.r., Armstrong, M.L., Reisdorph, N., McQueen, M.B., Chonchol, M.B., Seals, D.R., Chronic nicotinamide riboside supplementation is well-tolerated and effectively elevates NAD+ in healthy middle-aged and older adults. 2018, University of Colorado Boulder.
  15. Bieganowski, P. and C. Brenner, Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell, 2004. 117(4): p. 495-502.
  16. Guest, J., et al., Changes in oxidative damage, inflammation and [NAD(H)] with age in cerebrospinal fluid. PLoS One, 2014. 9(1): p. e85335.
  17. Ratajczak, J., et al., NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells. Nat Commun, 2016. 7: p. 13103.
  18. Zhu, X.H., et al., In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences. Proc Natl Acad Sci U S A, 2015. 112(9): p. 2876-81.


Shipping
 This item Ships to 
Delivery

Estimated between  and

Will usually ship within 1 business day.

   

Please allow 10 days for your order to arrive. We source products from all over the world to bring you epic offers and the lowest prices. This means sometimes you have to wait a little longer to get your order but it's always worth it!

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap!

Here are 5 more great reasons to buy from us:

   

We Put Our Customers First to us. If it doesn't fit, it breaks, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund you every cent.

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap!

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Shoptimized is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone either.

Take an active role in helping maintain your health, longer [1-3]. TRU NIAGEN® PRO delivers the highest dose of nicotinamide riboside (NR) per capsule available today. It’s key ingredient is backed by multiple published human trials, and is clinically proven to increase nicotinamide adenine dinucleotide (NAD)[4-6], the critical catalyst that powers metabolism and helps maintain healthy cellular function.*

Adults take One capsule per day or as recommended by your healthcare professional.

Serving Size: 1 Vegetarian Capsule

Amount Per Serving
NIAGEN® ... 300mg
(nicotinamide riboside chloride)

Other Ingredients: Microcrystalline Cellulose, Hypromellose (Vegetarian Capsule).

NIAGEN® and TRU NIAGEN® are trademarks of ChromaDex, Inc.
If you are pregnant, nursing, or taking any medications, please seek the advice of a healthcare professional prior to use. Not intended for use by children under 18. Store in original container in a cool, dry place.

NAD has been shown to decline with age [7, 8] and metabolic stress [9-12]. It has also been shown to help support many aspects of healthy aging.

Tru Niagen Pro provides daily cellular care to help you age better® and live better, including:

  • Replenishing NAD levels[4, 6, 13, 14]*
  • Increasing cellular energy production[14]*
  • Promoting healthy cellular metabolism[15-17]*
  • Promoting cellular repair[7, 15, 17, 18]*
  • Supporting healthy aging[4, 6, 13, 14]*
References
  1. Rajman, L., K. Chwalek, and D.A. Sinclair, Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell Metab, 2018. 27(3): p. 529-547.
  2. Verdin, E., NAD(+) in aging, metabolism, and neurodegeneration. Science, 2015. 350(6265): p. 1208-13.
  3. Yoshino, J., J.A. Baur, and S.I. Imai, NAD(+) Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab, 2018. 27(3): p. 513-528.
  4. Airhart, S.E., et al., An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers. PLoS One, 2017. 12(12): p. e0186459.
  5. Martens, C.R., et al., Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults. Nat Commun, 2018. 9(1): p. 1286.
  6. Trammell, S.A., et al., Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nat Commun, 2016. 7: p. 12948.
  7. Massudi, H., et al., Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One, 2012. 7(7): p. e42357.
  8. Zhou, C.C., et al., Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. Br J Pharmacol, 2016. 173(15): p. 2352-68.
  9. Canto, C., et al., The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metab, 2012. 15(6): p. 838-47.
  10. Gariani, K., et al., Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice. Hepatology, 2016. 63(4): p. 1190-204.
  11. Seyssel, K., et al., Regulation of energy metabolism and mitochondrial function in skeletal muscle during lipid overfeeding in healthy men. J Clin Endocrinol Metab, 2014. 99(7): p. E1254-62.
  12. Wang, S., et al., Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1alpha/mitochondrial biosynthesis pathway. Redox Biol, 2018. 17: p. 89-98.
  13. Dollerup, O.L., et al., A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects. Am J Clin Nutr, 2018.
  14. Martens, C.R., Denman, B.A., Mazzo, M.r., Armstrong, M.L., Reisdorph, N., McQueen, M.B., Chonchol, M.B., Seals, D.R., Chronic nicotinamide riboside supplementation is well-tolerated and effectively elevates NAD+ in healthy middle-aged and older adults. 2018, University of Colorado Boulder.
  15. Bieganowski, P. and C. Brenner, Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell, 2004. 117(4): p. 495-502.
  16. Guest, J., et al., Changes in oxidative damage, inflammation and [NAD(H)] with age in cerebrospinal fluid. PLoS One, 2014. 9(1): p. e85335.
  17. Ratajczak, J., et al., NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells. Nat Commun, 2016. 7: p. 13103.
  18. Zhu, X.H., et al., In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences. Proc Natl Acad Sci U S A, 2015. 112(9): p. 2876-81.


Shipping
This item Ships to   
Delivery

Estimated between  and

Will usually ship within 1 business day.

   

Please allow 10 days for your order to arrive. We source products from all over the world to bring you epic offers and the lowest prices. This means sometimes you have to wait a little longer to get your order but it's always worth it!

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap!

Here are 5 more great reasons to buy from us:

   

We Put Our Customers First to us. If it doesn't fit, it breaks, you've changed your mind or for no reason whatsoever simply send it back to us and we'll cheerfully refund you every cent.

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. We'll get you a replacement or refund in a snap!

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Shoptimized is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone either.

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